Tebufenozide

From WikiMD's Wellness Encyclopedia


Overview[edit | edit source]

Tebufenozide is a chemical compound used as an insecticide, primarily in agriculture. It belongs to the class of insect growth regulators (IGRs) and is specifically known for its action as a moulting accelerator in Lepidoptera larvae. Tebufenozide mimics the action of the natural insect hormone ecdysone, which is responsible for regulating the process of moulting and metamorphosis in insects.

Chemical Properties[edit | edit source]

Tebufenozide is a diacylhydrazine compound with the chemical formula C22H28N2O2. It is a white crystalline solid with a molecular weight of 352.47 g/mol. The compound is relatively stable under normal environmental conditions and has a low solubility in water, which affects its environmental persistence and mobility.

Mode of Action[edit | edit source]

Tebufenozide acts by binding to the ecdysone receptor in susceptible insects, leading to premature and incomplete moulting. This disrupts the normal development of the insect, ultimately causing death. The specificity of tebufenozide for the ecdysone receptor in Lepidoptera makes it particularly effective against caterpillar pests while having minimal impact on non-target organisms, including beneficial insects and humans.

Applications[edit | edit source]

Tebufenozide is used in the control of various caterpillar pests in crops such as cotton, corn, soybeans, fruits, and vegetables. It is applied as a foliar spray and is valued for its selective action and low toxicity to mammals and other non-target species.

Environmental Impact[edit | edit source]

Due to its selective mode of action, tebufenozide is considered to have a favorable environmental profile. It poses a low risk to pollinators and other beneficial insects. However, as with any pesticide, careful management and adherence to recommended application rates are essential to minimize any potential environmental impact.

Safety and Regulation[edit | edit source]

Tebufenozide has been evaluated by various regulatory agencies, including the United States Environmental Protection Agency (EPA) and the European Food Safety Authority (EFSA). It is approved for use in many countries, subject to specific regulations regarding its application and maximum residue limits in food products.

Also see[edit | edit source]



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