Technetium tc 99m generator

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Technetium Tc 99m Generator is a device used in nuclear medicine to extract the radioisotope Technetium-99m (Tc-99m) from a source of Molybdenum-99 (Mo-99). The generator, often referred to as a "moly cow," is a crucial component in many medical imaging procedures.

Overview[edit | edit source]

The Technetium Tc 99m Generator operates on the principle of radioactive decay. The parent isotope, Mo-99, decays to Tc-99m through a process known as beta decay. This decay process occurs with a half-life of 66 hours, allowing the generator to produce Tc-99m over a period of one to two weeks.

Operation[edit | edit source]

The generator contains a column of alumina (aluminium oxide), which is loaded with Mo-99. As the Mo-99 decays, it forms Tc-99m, which adheres to the alumina. The Tc-99m is then eluted, or washed out, from the column using a saline solution. This elution process can be performed multiple times per day, providing a continuous source of Tc-99m for medical imaging procedures.

Applications[edit | edit source]

Tc-99m is used in a variety of medical imaging procedures due to its ideal physical properties. It emits low energy gamma rays, which can be easily detected by a gamma camera. Additionally, Tc-99m has a short half-life of 6 hours, minimizing the radiation dose to the patient. It is used in procedures such as bone scans, cardiac imaging, and cancer detection.

Safety and Regulations[edit | edit source]

The use of Technetium Tc 99m Generators is regulated by the Nuclear Regulatory Commission (NRC) in the United States, and by similar bodies in other countries. These regulations ensure the safe handling and disposal of radioactive materials.

See Also[edit | edit source]




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Contributors: Prab R. Tumpati, MD