Teclozan

Teclozan

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Chemical structure of Teclozan

Teclozan is an antiprotozoal medication primarily used in the treatment of intestinal infections caused by protozoa. It is known for its efficacy against certain types of amoebiasis and giardiasis.

Mechanism of Action

Teclozan works by interfering with the metabolic processes of protozoa, leading to their death. It targets the DNA synthesis within the protozoal cells, thereby inhibiting their ability to reproduce and spread within the host's gastrointestinal tract.

Clinical Uses

Teclozan is indicated for the treatment of:

• Amoebiasis: An infection caused by the Entamoeba histolytica parasite, which can lead to dysentery and liver abscesses.
• Giardiasis: An infection caused by the Giardia lamblia parasite, resulting in diarrhea, abdominal pain, and malabsorption.

Dosage and Administration

The dosage of Teclozan varies depending on the severity of the infection and the patient's age and weight. It is typically administered orally in tablet form. Patients are advised to follow the prescribed dosage regimen to ensure the effectiveness of the treatment.

Side Effects

Common side effects of Teclozan may include:

• Nausea
• Vomiting
• Diarrhea
• Abdominal pain

In rare cases, patients may experience allergic reactions such as rash, itching, or swelling.

Contraindications

Teclozan is contraindicated in patients with:

• Known hypersensitivity to the drug
• Severe liver impairment

Related Pages

• Antiprotozoal
• Amoebiasis
• Giardiasis
• Intestinal infections