Tenocyclidine

From WikiMD's Wellness Encyclopedia

Tenocyclidine (also known as TCP) is a dissociative anesthetic drug with hallucinogenic effects. It is similar in effects to phencyclidine but is considerably more potent due to increased stimulation of the NMDA receptor.

History[edit | edit source]

Tenocyclidine was discovered in the 1950s during research into analogs of phencyclidine. It was found to be around 3-5 times more potent than PCP and was considered for medical use in humans due to its increased potency and lower dosage requirement, but its development was dropped due to the high incidence of dysphoria and psychosis-like side effects.

Pharmacology[edit | edit source]

Like other dissociatives, tenocyclidine acts as an NMDA receptor antagonist. However, unlike most dissociatives, it also acts as a Dopamine reuptake inhibitor, which may explain some of its stimulating effects.

Effects[edit | edit source]

The effects of tenocyclidine are similar to those of other dissociatives. Users may experience feelings of detachment or disconnection from their bodies and surroundings, as well as hallucinations. However, due to its potency, the risk of overdose and serious side effects is higher than with other dissociatives.

Legal status[edit | edit source]

Tenocyclidine is a Schedule I controlled substance in the United States, meaning it is illegal to manufacture, buy, possess, or distribute without a license from the Drug Enforcement Administration.

See also[edit | edit source]

References[edit | edit source]


Tenocyclidine Resources
Wikipedia
WikiMD
Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD

Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD

WikiMD's Wellness Encyclopedia

Let Food Be Thy Medicine
Medicine Thy Food - Hippocrates

Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.

Contributors: Prab R. Tumpati, MD