Tetrahydrofuranylfentanyl

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Tetrahydrofuranylfentanyl

Tetrahydrofuranylfentanyl (THF-F or THFF) is a potent opioid analgesic drug that is an analog of fentanyl.

History

Tetrahydrofuranylfentanyl was first synthesized in the late 20th century, following the development of the parent compound, fentanyl. It is part of a series of fentanyl analogs, which vary in potency and effects.

Pharmacology

Like other fentanyl analogs, tetrahydrofuranylfentanyl acts as a potent agonist at the mu-opioid receptor. This receptor is a key site of action for opioids and is responsible for their analgesic effects. The potency of tetrahydrofuranylfentanyl is similar to that of fentanyl itself.

Effects

The effects of tetrahydrofuranylfentanyl are similar to those of other opioids. These include analgesia, sedation, euphoria, and respiratory depression. Due to its high potency, the risk of overdose is significant, especially when the drug is used recreationally or without medical supervision.

Legal status

Tetrahydrofuranylfentanyl is a controlled substance in many countries, including the United States, where it is classified as a Schedule I drug under the Controlled Substances Act. This means that it has a high potential for abuse, no currently accepted medical use in treatment in the United States, and a lack of accepted safety for use under medical supervision.

See also

• Fentanyl
• Opioid
• Controlled Substances Act