The Last Days of Smallpox

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Last Days of Smallpox

The Last Days of Smallpox marks a significant period in medical history, culminating in the eradication of smallpox, a deadly disease that plagued humanity for centuries. This article delves into the final stages of the battle against smallpox, highlighting the global efforts, challenges, and milestones that led to its eradication.

Background[edit | edit source]

Smallpox was a highly contagious and deadly disease caused by the variola virus. Its history is marked by devastating outbreaks that resulted in the death and disfigurement of millions worldwide. The disease was characterized by fever, malaise, and a distinctive rash that turned into pus-filled sores. Smallpox had a high mortality rate, and survivors often bore significant scars.

Global Eradication Efforts[edit | edit source]

The journey to eradicate smallpox began in earnest in the 20th century. The World Health Organization (WHO) launched an intensified plan in 1967, aiming to eliminate smallpox through widespread vaccination campaigns. This global effort was unprecedented in its scale and required cooperation among nations, healthcare workers, and volunteers.

Vaccination Campaigns[edit | edit source]

The cornerstone of the eradication strategy was the use of the smallpox vaccine. Unlike other diseases, smallpox had no animal reservoir, meaning it could only spread among humans. This fact made vaccination an effective strategy for eradication. The vaccine, derived from the related cowpox virus, provided immunity without causing the disease itself.

Surveillance and Containment[edit | edit source]

Alongside vaccination, surveillance and containment were crucial in the fight against smallpox. This strategy involved quickly identifying new cases and vaccinating everyone in the surrounding area to prevent the spread. This method, known as "ring vaccination," proved effective in containing outbreaks.

The Last Known Cases[edit | edit source]

The final push towards eradication saw health workers tracking down the last cases of smallpox in remote areas. The last naturally occurring case was reported in Somalia in 1977, in an individual named Ali Maow Maalin. Following this, intensive surveillance continued for several more years to ensure no hidden cases remained.

Declaration of Eradication[edit | edit source]

In 1980, the WHO officially declared smallpox eradicated, marking the first time in history that a disease had been eliminated through human efforts. This monumental achievement demonstrated the potential of global cooperation and vaccination in combating infectious diseases.

Legacy and Continuing Impact[edit | edit source]

The eradication of smallpox has left a lasting legacy on global health, influencing strategies for combating other infectious diseases. It also highlighted the importance of vaccination and the potential for eradicating other diseases. However, the story of smallpox continues to serve as a reminder of the threats posed by infectious diseases and the ongoing need for vigilance and preparedness.


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Contributors: Prab R. Tumpati, MD