Threohydrobupropion

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Threohydrobupropion is a metabolite of the antidepressant drug bupropion. It is formed in the body after consumption of bupropion and is believed to contribute to the drug's antidepressant effects.

Pharmacology[edit | edit source]

Threohydrobupropion is a metabolite of bupropion, an antidepressant drug. It is formed in the body after consumption of bupropion. Threohydrobupropion is believed to contribute to the drug's antidepressant effects.

Metabolism[edit | edit source]

Threohydrobupropion is formed in the body through the metabolism of bupropion. This process involves the enzyme CYP2B6, which converts bupropion into threohydrobupropion.

Clinical significance[edit | edit source]

Threohydrobupropion is believed to contribute to the antidepressant effects of bupropion. It is also a significant metabolite in terms of plasma levels, and its levels can be affected by genetic variations in CYP2B6.

See also[edit | edit source]

References[edit | edit source]


Threohydrobupropion Resources
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Contributors: Prab R. Tumpati, MD