Tigilanol tiglate
Tigilanol tiglate is a pharmaceutical drug used in the treatment of canine mast cell tumors. It is a small molecule isolated from the seed of the Australian blushwood tree (Hylandia dockrillii).
History[edit | edit source]
Tigilanol tiglate was developed by QBiotics, a life sciences company. The drug was approved by the European Medicines Agency (EMA) in 2020 for the treatment of non-resectable mast cell tumors in dogs.
Mechanism of Action[edit | edit source]
Tigilanol tiglate works by activating Protein Kinase C (PKC), which leads to a series of events causing tumor cells to die and the body to reject the tumor. The drug is injected directly into the tumor, causing it to become necrotic and eventually slough off.
Side Effects[edit | edit source]
Common side effects of tigilanol tiglate include pain or discomfort at the injection site, vomiting, and diarrhea. More serious side effects can include severe skin reactions and systemic allergic reactions.
Veterinary Use[edit | edit source]
Tigilanol tiglate is used in veterinary medicine for the treatment of mast cell tumors in dogs. It is particularly useful for tumors that cannot be surgically removed.
Human Use[edit | edit source]
While tigilanol tiglate is currently only approved for use in dogs, research is ongoing into its potential use in humans. Early studies suggest it may be effective in treating certain types of skin cancer.
See Also[edit | edit source]
| Tigilanol tiglate Resources | |
|---|---|
|
 |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
