Tissue-agnostic cancer drug
Tissue-agnostic cancer drugs are antineoplastic drugs that treat cancers based on the mutations that they display, instead of the tissue type in which they appear.[1][2][3] Tissue-agnostic drugs include Pembrolizumab (Keytruda) and Larotrectinib (Vitrakvi).[2] [4]
History[edit | edit source]
Petrolizumab was approved by the US Food and Drug Administration In May 2017.[5]
Larotrectinib was approved by the FDA in November, 2018.[5]
Loxo-292 received priority review in September 2018.[5]
Other drugs under development include Entrectinib, BLU-667, Loxo-195 and Anti-ERBB3 antibody.[5]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD
