Tissue space

Tissue space refers to the interstitial space, also known as the tissue fluid or interstitial fluid space, located between the cells of the body's tissues. This space is filled with a fluid matrix that provides a supportive environment for cells, allowing for the exchange of nutrients, waste products, and other molecules.

Composition

The tissue space is filled with interstitial fluid, a solution that bathes and surrounds the cells of multicellular animals. It is the main component of the extracellular fluid, which also includes plasma and transcellular fluid. The interstitial fluid is derived from blood plasma and is constantly refreshed by the blood capillaries.

Function

The primary function of the tissue space is to provide a supportive environment for cells. It allows for the exchange of nutrients, waste products, and other molecules between the blood and the cells. This exchange is facilitated by the capillary wall, which acts as a semi-permeable barrier.

The tissue space also plays a crucial role in the body's immune response. White blood cells can leave the blood vessels and move into the tissue space to reach the site of an infection.

Clinical significance

Changes in the volume or composition of the interstitial fluid in the tissue space can have significant clinical implications. For example, edema is a condition characterized by an excessive accumulation of fluid in the tissue space, leading to swelling. It can be caused by various conditions, including heart failure, kidney disease, and liver disease.

On the other hand, dehydration can lead to a decrease in the volume of interstitial fluid, affecting the delivery of nutrients to cells and the removal of waste products.

See also

• Extracellular fluid
• Interstitial fluid
• Capillary
• Edema
• Dehydration