Topical hydrocortisone
Topical Hydrocortisone[edit | edit source]
Topical hydrocortisone is a corticosteroid medication used to treat a variety of skin conditions. It is applied directly to the skin to reduce inflammation, swelling, and irritation. Hydrocortisone is a synthetic form of cortisol, a hormone naturally produced by the adrenal gland.
Uses[edit | edit source]
Topical hydrocortisone is commonly used to treat conditions such as eczema, psoriasis, dermatitis, allergic reactions, and rashes. It works by suppressing the immune response and reducing inflammation in the affected area.
Mechanism of Action[edit | edit source]
Hydrocortisone acts by binding to glucocorticoid receptors in the skin, leading to a decrease in the production of inflammatory mediators. This results in reduced redness, swelling, and itching. The drug mimics the action of cortisol, which is involved in the body's response to stress and inflammation.
Side Effects[edit | edit source]
While topical hydrocortisone is generally safe when used as directed, it can cause side effects, especially with prolonged use. Common side effects include skin thinning, stretch marks, and increased susceptibility to skin infections. In rare cases, systemic absorption can lead to more serious effects such as Cushing's syndrome.
Application[edit | edit source]
Topical hydrocortisone is available in various forms, including creams, ointments, and lotions. It is typically applied to the affected area one to four times daily, depending on the severity of the condition and the strength of the preparation.
Precautions[edit | edit source]
Patients are advised to use topical hydrocortisone only as prescribed by a healthcare provider. It should not be used on broken or infected skin unless directed by a doctor. Long-term use should be avoided to prevent potential side effects.
Related Pages[edit | edit source]
References[edit | edit source]
Chemical structure of cortisol
Overview of glucocorticoid-associated side effects
Annotated chemical structure of hydrocortisone
Tube of hydrocortisone cream
Topical hydrocortisone cream with neomycin
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