Tracy Putnam

Tracy Jackson Putnam

Born	April 14, 1894
Birth place	Boston, Massachusetts, USA
Died	March 29, 1975
Nationality	American
Known for	Discovery of phenytoin

Tracy Jackson Putnam (April 14, 1894 – March 29, 1975) was an American neurologist and researcher best known for his co-discovery of phenytoin, an anticonvulsant drug used in the treatment of epilepsy. His work significantly advanced the field of neurology and provided a foundation for modern epilepsy treatment.

Early Life and Education

Tracy Putnam was born in Boston, Massachusetts. He attended Harvard University, where he completed his undergraduate studies. He then pursued a medical degree at Harvard Medical School, graduating in 1920. Following his graduation, Putnam completed his internship and residency in neurology, developing a keen interest in the treatment of neurological disorders.

Career

Putnam began his career at the Peter Bent Brigham Hospital in Boston, where he worked under the mentorship of prominent neurologists. In 1930, he joined the faculty at Harvard Medical School as an instructor in neurology. His research focused on the mechanisms of epilepsy and the development of effective treatments.

In 1937, Putnam moved to the Boston City Hospital and later to the New York Neurological Institute at Columbia University, where he continued his groundbreaking research on anticonvulsant drugs.

Discovery of Phenytoin

In collaboration with H. Houston Merritt, Putnam conducted a series of experiments to identify compounds that could effectively control seizures without the sedative effects of phenobarbital, the standard treatment at the time. Their research led to the discovery of phenytoin (marketed as Dilantin), which was found to be effective in controlling seizures with minimal sedation.

Phenytoin's introduction revolutionized the treatment of epilepsy, providing a safer and more effective option for patients. It remains one of the most widely used anticonvulsants today.

Later Life and Legacy

After his success with phenytoin, Putnam continued to contribute to the field of neurology through research and teaching. He held various academic positions and was involved in numerous professional organizations dedicated to neurological research.

Putnam's work laid the groundwork for future advancements in epilepsy treatment and inspired generations of neurologists. He passed away on March 29, 1975, leaving behind a legacy of innovation and dedication to improving patient care.

Also see

• Epilepsy
• Anticonvulsant
• H. Houston Merritt
• Phenobarbital
• Harvard Medical School