Transposases

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Transposases Enzymes that recombine DNA segments by a process which involves the formation of a synapse between two DNA helices, the cleavage of single strands from each DNA helix and the ligation of a DNA strand from one DNA helix to the other. The resulting DNA structure is called a Holliday junction which can be resolved by DNA replication or by Holliday junction resolvases.

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Contributors: Prab R. Tumpati, MD