Tremorine

Tremorine

Tremorine is a chemical compound used in scientific research to induce tremors in laboratory animals, particularly rodents. It is often used in the study of Parkinson's disease and other neurological disorders that cause tremors.

Chemical Structure

Tremorine is a tertiary amine with the chemical formula C10H17N. It is a colorless liquid at room temperature and has a strong, unpleasant odor. The compound is soluble in water and most organic solvents.

Mechanism of Action

The exact mechanism of action of tremorine is not fully understood. However, it is believed to act on the central nervous system (CNS), specifically the basal ganglia, a group of structures in the brain involved in the control of voluntary motor movements. Tremorine is thought to disrupt the normal functioning of these structures, leading to the characteristic tremors.

Use in Research

Tremorine is primarily used in the study of Parkinson's disease, a neurodegenerative disorder characterized by tremors, rigidity, and bradykinesia (slowness of movement). By inducing tremors in laboratory animals, researchers can study the effects of potential treatments for Parkinson's disease.

In addition to Parkinson's disease, tremorine is also used in the study of other neurological disorders that cause tremors, such as essential tremor and multiple sclerosis.

Safety

Tremorine is a potent compound and should be handled with care. It can cause skin and eye irritation, and prolonged exposure can lead to respiratory problems. Ingestion or inhalation of tremorine can cause tremors and other neurological symptoms.

See Also

• Parkinson's disease
• Essential tremor
• Multiple sclerosis
• Basal ganglia
• Tremors

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