Tropicamide/phenylephrine

Tropicamide/Phenylephrine is a combination medication used in the field of ophthalmology for pupil dilation, a process known as mydriasis. It is a mixture of two active ingredients: Tropicamide and Phenylephrine.

Composition

The medication is composed of two active ingredients. Tropicamide is a muscarinic antagonist that works by blocking the responses to acetylcholine, a neurotransmitter in the body. Phenylephrine is a selective α1-adrenergic receptor agonist used primarily as a decongestant, as an agent to dilate the pupil, and to increase blood pressure.

Uses

Tropicamide/Phenylephrine is primarily used by ophthalmologists for diagnostic purposes. It is used to dilate the pupil in order to allow a more thorough examination of the interior structures of the eye, including the lens, retina, and optic nerve. This can aid in the diagnosis of a variety of conditions, including glaucoma, macular degeneration, and retinal detachment.

Side Effects

As with any medication, Tropicamide/Phenylephrine can cause side effects. These may include blurred vision, stinging or burning in the eye, increased sensitivity to light, and temporary changes in color vision. Systemic side effects can occur, particularly with phenylephrine, and may include high blood pressure, fast heart rate, and irregular heart rhythm.

Contraindications

Tropicamide/Phenylephrine should not be used in patients with known hypersensitivity to either component of the medication. It should also be used with caution in patients with high blood pressure, heart disease, or narrow-angle glaucoma.

Interactions

Tropicamide/Phenylephrine may interact with other medications, including monoamine oxidase inhibitors (MAOIs), tricyclic antidepressants, and other drugs that affect the sympathetic nervous system.

See Also

• Ophthalmology
• Mydriasis
• Glaucoma
• Macular degeneration
• Retinal detachment