Tulobuterol
A bronchodilator used in the treatment of asthma and COPD
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Tulobuterol is a bronchodilator medication used in the management of asthma and chronic obstructive pulmonary disease (COPD). It is a beta-2 adrenergic receptor agonist that helps to relax the muscles in the airways, improving breathing in patients with obstructive airway diseases.
Pharmacology[edit | edit source]
Tulobuterol works by stimulating beta-2 adrenergic receptors in the lungs, leading to the relaxation of bronchial smooth muscle. This action helps to open up the airways, making it easier for patients to breathe. The drug is typically administered via a transdermal patch, which provides a steady release of medication over time.
Administration[edit | edit source]
Tulobuterol is commonly administered using a transdermal patch known as the Hokunalin tape. This method of delivery allows for continuous absorption of the drug through the skin, maintaining stable blood levels and providing prolonged bronchodilation.
Synthesis[edit | edit source]
The synthesis of tulobuterol involves several chemical reactions, starting from basic organic compounds. The process includes the formation of the tert-butylamino group and the attachment of the 2-chlorophenyl group to the propan-2-ol backbone.
Side Effects[edit | edit source]
Common side effects of tulobuterol include tremor, headache, and palpitations. As with other beta-2 agonists, there is a risk of tachycardia and hypokalemia. Patients are advised to monitor for any adverse reactions and consult their healthcare provider if they experience significant side effects.
Related pages[edit | edit source]
Tulobuterol
Tulobuterol ball-and-stick model
Hokunalin tape
Tulobuterol synthesis
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