URB754

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URB754

URB754 is a chemical compound that is used in scientific research. It is an inhibitor of the enzyme monoacylglycerol lipase (MAGL), which is involved in the metabolism of the endocannabinoid 2-arachidonoylglycerol (2-AG). URB754 is used to increase the levels of 2-AG in the body, which can have various effects on the endocannabinoid system.

Chemistry

URB754 is a urea derivative, with the chemical formula C23H24N2O4. It is a white, crystalline solid at room temperature. The compound is highly soluble in organic solvents such as dimethyl sulfoxide (DMSO), but less so in water.

Pharmacology

URB754 acts as an inhibitor of the enzyme MAGL, which is responsible for the breakdown of the endocannabinoid 2-AG. By inhibiting this enzyme, URB754 increases the levels of 2-AG in the body. This can have a variety of effects, as 2-AG is involved in a number of physiological processes, including pain sensation, mood, and appetite.

Research

URB754 has been used in a number of scientific studies to investigate the role of the endocannabinoid system in various conditions. For example, it has been used in research into pain management, as increasing levels of 2-AG has been shown to reduce pain sensation. It has also been used in studies into the effects of cannabinoids on appetite and mood.

Safety

As a research chemical, URB754 is not intended for human consumption. Its safety profile has not been fully established, and it should be handled with care.

See also

• Endocannabinoid system
• 2-Arachidonoylglycerol
• Monoacylglycerol lipase