VD/VT

Tuberomammillary nucleus is a portion of the hypothalamus that is responsible for the release of histamine to the rest of the brain. It is the only source of histamine neurons in the brain, and it plays a crucial role in the regulation of the sleep-wake cycle and arousal.

Function[edit | edit source]

The tuberomammillary nucleus is involved in several important functions in the body. It is responsible for the release of histamine, which is a neurotransmitter that plays a crucial role in the regulation of the sleep-wake cycle, arousal, and other cognitive functions. The tuberomammillary nucleus also plays a role in the regulation of body temperature, appetite, and energy balance.

Anatomy[edit | edit source]

The tuberomammillary nucleus is located in the posterior hypothalamus, near the mammillary bodies. It is composed of histaminergic neurons, which are neurons that produce and release histamine. These neurons project to various areas of the brain, including the cortex, hippocampus, and amygdala, where they play a role in the regulation of various cognitive functions.

Clinical significance[edit | edit source]

Alterations in the function of the tuberomammillary nucleus and its histaminergic neurons have been implicated in several neurological and psychiatric disorders, including narcolepsy, Parkinson's disease, Alzheimer's disease, and depression. In particular, a decrease in histaminergic activity has been associated with increased sleepiness in narcolepsy and cognitive impairment in Alzheimer's disease.

References[edit | edit source]

VD/VT Resources
Need Help Finding a Doctor? Need help finding a doctor or specialist anywhere in the world? Explore our world directory. WikiMD's DocFinder can assist you in locating millions of physicians.	Medical Knowledge Access the latest research - Most recent articles Ongoing trials.