Vaginitis emphysematosa

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Vaginitis emphysematosa is a rare, benign vaginal cyst identified in 173 cases.[1][2][3][4] Women that have been affected were 42 to 65 years old.[2] The cysts appear grouped but defined from one another, smooth, and can be as large as 2 cm.[1] Symptoms included: vaginal discharge, itching, sensation of pressure, appearance of nodules, and sometimes a "popping sound".[1][5] The cause is unknown. Histological examination showed the cysts contained pink hyalin-like material, foreign body-type giant cells in the cyst's wall, with chronic inflammatory cell fluid. The gas-filled cysts are identified with CT imaging. The gas contained in the cysts has been analysed and consists of nitrogen, oxygen, argon, carbon dioxide, and sulfur dioxide.[1] Treatment may not be required and no complications follow the resolution of the cysts.[2] It may be associated with immunosuppresion, trichomonsis, or Haemophilus vaginalis infection.[1][6] Vaginitis emphysemotosa is characterized by gas-filled cysts in the vaginal wall. The first mention of the cyst was in 1877 by Zweifel.[1][4]

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Contributors: Prab R. Tumpati, MD