Valerenol
Valerenol[edit | edit source]
Valerenol is a sesquiterpenoid alcohol that is primarily found in the essential oil of the valerian plant, Valeriana officinalis. It is one of the active constituents believed to contribute to the sedative and anxiolytic effects of valerian root, which has been used in traditional medicine for centuries.
Chemical Structure and Properties[edit | edit source]
Valerenol is classified as a sesquiterpene, which is a type of terpene consisting of three isoprene units. Its chemical formula is C15H24O, and it has a molecular weight of 220.35 g/mol. The compound is characterized by its alcohol functional group, which contributes to its solubility in organic solvents.
Sources[edit | edit source]
Valerenol is extracted from the roots of the valerian plant, which is native to Europe and parts of Asia. The plant is cultivated for its medicinal properties, and the essential oil is obtained through steam distillation of the dried roots.
Pharmacological Effects[edit | edit source]
Valerenol, along with other compounds such as valerenic acid and valtrate, is thought to interact with the GABA (gamma-aminobutyric acid) system in the brain. This interaction is believed to enhance the inhibitory effects of GABA, leading to a calming effect on the nervous system. As a result, valerenol is often associated with the sedative and anxiolytic properties of valerian root extracts.
Uses in Medicine[edit | edit source]
Valerenol is primarily used in the form of valerian root extracts, which are available as dietary supplements. These supplements are commonly used to promote relaxation, improve sleep quality, and reduce anxiety. While valerian root is generally considered safe, its efficacy can vary, and more research is needed to fully understand the role of valerenol in these effects.
Safety and Side Effects[edit | edit source]
Valerenol, as part of valerian root extracts, is generally well-tolerated. However, some individuals may experience mild side effects such as headache, dizziness, or gastrointestinal disturbances. It is important to consult with a healthcare provider before using valerian supplements, especially for individuals who are pregnant, nursing, or taking other medications.
Also see[edit | edit source]
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