Tocofersolan

Tocofersolan, also known as tocophersolan or tocophersol, is a water-soluble form of vitamin E that is used in medical settings for various purposes. It is a derivative of alpha-tocopherol, which is a natural form of vitamin E found in foods such as nuts, seeds, and vegetable oils.

Medical Uses

Tocofersolan is commonly used as an intravenous formulation of vitamin E for patients who have malabsorption issues or are unable to take oral supplements. It is also used in the treatment of vitamin E deficiency, which can occur in individuals with certain medical conditions or those who are unable to absorb fat-soluble vitamins properly.

Pharmacokinetics

When administered intravenously, tocophersolan is rapidly absorbed into the bloodstream and distributed to various tissues in the body. It is metabolized in the liver and excreted primarily in the urine.

Adverse Effects

Common side effects of tocophersolan include nausea, vomiting, and diarrhea. In rare cases, allergic reactions such as rash or itching may occur. It is important to consult a healthcare provider if any adverse effects are experienced.

Interactions

Tocofersolan may interact with certain medications, such as anticoagulants or antiplatelet drugs. It is important to inform your healthcare provider about all medications you are taking before starting tocophersolan therapy.

References

• PubMed article on tocophersolan
• Drugs.com information on tocophersolan