Verapamil hcl

Verapamil HCl is a medication used in the treatment of various cardiovascular conditions. It belongs to a class of drugs known as calcium channel blockers, which work by relaxing the muscles of the heart and blood vessels.

Pharmacology

Verapamil HCl works by inhibiting the influx of calcium ions into cardiac and smooth muscle cells, leading to relaxation and vasodilation. It also has direct effects on the electrical conduction system of the heart, slowing the passage of electrical signals and thus reducing heart rate.

Medical Uses

Verapamil HCl is used to treat a variety of cardiovascular conditions, including hypertension, angina pectoris, and certain types of arrhythmia. It is also used off-label in the prevention of migraine headaches.

Side Effects

Common side effects of Verapamil HCl include dizziness, slow heart rate, and constipation. More serious side effects can include low blood pressure, heart failure, and severe allergic reactions.

Contraindications

Verapamil HCl is contraindicated in individuals with certain heart conditions, including sick sinus syndrome and second- or third-degree atrioventricular block, unless they have a functioning artificial pacemaker. It is also contraindicated in severe left ventricular dysfunction and hypotension.

Interactions

Verapamil HCl can interact with a number of other medications, including beta blockers, digoxin, and certain statins. These interactions can lead to increased risk of side effects or decreased effectiveness of the medications.

See Also

• Calcium channel blocker
• Hypertension
• Angina pectoris
• Arrhythmia