Vero

Vero cells are a lineage of cells used in cell cultures. The 'Vero' lineage was isolated from kidney epithelial cells extracted from an African green monkey (Chlorocebus sp.; often incorrectly cited as Cercopithecus aethiops, a separate species of monkey). The lineage was developed on 27 March 1962, by Yasumura and Kawakita at the Chiba University in Chiba, Japan.

History

The Vero cell lineage was isolated from the kidney of an African green monkey by Y. Yasumura and Y. Kawakita in Chiba University, Japan, in 1962. The name "Vero" is derived from the fact that the cells were isolated from a verda reno, which is Esperanto for "green kidney".

Characteristics

Vero cells are epithelial in morphology and are unable to produce interferon. They also lack the enzyme necessary for the incorporation of uracil into viral RNA, making them useful for detecting a wide range of viruses.

Uses

Vero cells are used for many purposes in biological research, including:

• The production of polio vaccines
• The study of the growth of viruses and the effects of antiviral substances
• The development of new vaccines and drugs

See also

• Cell culture
• African green monkey
• Interferon
• Uracil
• Polio vaccine

References

Vero Resources
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