Vitamin K6
Vitamin K6 is a form of Vitamin K, a group of structurally similar, fat-soluble vitamins that are needed for the posttranslational modification of certain proteins, primarily required for blood coagulation but also involved in metabolic pathways in bone and other tissue.
Chemical Structure[edit | edit source]
Vitamin K6, like other forms of Vitamin K, is a fat-soluble vitamin. It is structurally similar to other forms of Vitamin K, with a 2-methyl-1,4-naphthoquinone nucleus and a side chain at the 3-position.
Function[edit | edit source]
Vitamin K6, like other forms of Vitamin K, is involved in the carboxylation of certain glutamate residues in proteins to form gamma-carboxyglutamate (Gla) residues. This modification allows the protein to bind calcium, an essential event in the blood clotting cascade.
Sources[edit | edit source]
Vitamin K6 is not naturally occurring and is therefore not found in food sources. It is a synthetic form of Vitamin K, produced in a laboratory setting.
Deficiency[edit | edit source]
A deficiency in Vitamin K6, like other forms of Vitamin K, can lead to a coagulation defect, which can result in bleeding. This is because Vitamin K is necessary for the production of clotting factors in the liver.
Toxicity[edit | edit source]
Excessive intake of Vitamin K6 can lead to a condition known as vitamin K toxicity. This condition can cause a variety of symptoms, including jaundice, anemia, and brain damage.
See Also[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD