White Blood Cell

White blood cells (WBCs), also known as leukocytes or leucocytes, are the cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders. All white blood cells are produced and derived from multipotent cells in the bone marrow known as hematopoietic stem cells. Leukocytes are found throughout the body, including the blood and lymphatic system.

Types of White Blood Cells

There are five main types of white blood cells, which are distinguished by their physical and functional characteristics:

• Neutrophils - These are the most common type of white blood cell and are the first to respond to infections.
• Lymphocytes - These are the second most common type of white blood cell and are responsible for immune responses.
• Monocytes - These are the largest type of white blood cell and can differentiate into macrophages and myeloid lineage dendritic cells.
• Eosinophils - These are responsible for combating multicellular parasites and certain infections in vertebrates.
• Basophils - These are the least common type of white blood cell and are responsible for allergic and antigen response by releasing the chemical histamine causing the dilation of blood vessels.

Function

White blood cells are a key part of the body's immune system, as they help to fight off diseases and infections. They do this by attacking and destroying the organisms that cause disease. They also produce antibodies, which are proteins that help to neutralize harmful substances.

Production and Regulation

The production of white blood cells is regulated by the body's immune system. When the body is under attack from harmful substances, the immune system triggers the production of more white blood cells to fight off the infection.

See Also

• Red blood cell
• Platelet
• Hematopoiesis
• Immune system

References

White Blood Cell Resources
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