X-linked congenital generalized hypertrichosis

Alternate names

HTC2; CGH; HCG; Macias-Flores Garcia-Cruz Rivera syndrome; Congenital generalized hypertrichosis, Macias-Flores type; Macias Flores-Garcia Cruz-Rivera syndrome; Chromosome Xq27.1 interchromosomal insertion syndrome; Hypertrichosis congenital generalized X-linked

Definition

X-linked congenital generalized hypertrichosis is a rare congenital (present at birth) skin disease. It is characterized by hair overgrowth on the entire body in males, and mild and asymmetric hair overgrowth in females.

Cause

It is caused by a specific abnormality of the X chromosome.

Inheritance

Inheritance is X-linked.

Signs and symptoms

• It is characterized by hair overgrowth on the entire body in males, and mild and asymmetric hair overgrowth in females.
• It is associated with mild facial abnormalities (including nasal openings that are tipped upwards and moderate protrusion of the jaw) and occasional teeth anomalies and deafness.

Treatment

Treatment includes standard methods for hair removal such as shaving, laser hair removal, electrolysis, chemical methods and others.

NIH genetic and rare disease info

• NIH info on X-linked congenital generalized hypertrichosis

X-linked congenital generalized hypertrichosis is a rare disease.

X-linked congenital generalized hypertrichosis Resources
Need Help Finding a Doctor? Need help finding a doctor or specialist anywhere in the world? Explore our world directory. WikiMD's DocFinder can assist you in locating millions of physicians.	Medical Knowledge Access the latest research - Most recent articles Ongoing trials.

Translate to: East Asian 中文, 日本, 한국어, South Asian हिन्दी, Urdu, বাংলা, తెలుగు, தமிழ், ಕನ್ನಡ,
Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, European español, Deutsch, français, русский, português do Brasil, Italian, polski