Zenpep

Zenpep

Zenpep is a prescription medication used for the treatment of exocrine pancreatic insufficiency (EPI). It is a pancreatic enzyme replacement therapy (PERT) that helps in the digestion of fats, proteins, and carbohydrates in individuals with EPI. Zenpep contains a mixture of digestive enzymes, including lipases, proteases, and amylases, which are essential for proper digestion.

Mechanism of Action

Zenpep works by replacing the deficient pancreatic enzymes in individuals with EPI. In EPI, the pancreas does not produce enough enzymes to break down food properly, leading to malabsorption and nutrient deficiencies. Zenpep provides the necessary enzymes to aid in the digestion and absorption of nutrients from food.

Indications

Zenpep is indicated for the treatment of exocrine pancreatic insufficiency due to various conditions, including cystic fibrosis, chronic pancreatitis, and pancreatic cancer. It is prescribed to individuals who have difficulty digesting and absorbing nutrients from food due to insufficient pancreatic enzyme production.

Dosage and Administration

The dosage of Zenpep is individualized based on the patient's specific needs and the severity of their EPI. The recommended starting dose for adults is typically 500 lipase units per kilogram of body weight per meal, with adjustments made based on the patient's response. The capsules should be taken with meals or snacks and swallowed whole, without crushing or chewing.

Side Effects

Common side effects of Zenpep may include abdominal pain, diarrhea, constipation, nausea, and vomiting. These side effects are usually mild and transient. However, if they persist or worsen, it is important to consult a healthcare professional.

Precautions

Before taking Zenpep, it is important to inform your healthcare provider about any existing medical conditions, allergies, or medications you are currently taking. Zenpep may interact with certain medications, such as antacids, proton pump inhibitors, and H2 blockers, which can affect its effectiveness. It is also important to follow a balanced diet and adhere to any dietary restrictions recommended by your healthcare provider.