Zeteletinib
Zeteletinib is a novel cancer drug currently under investigation for its potential use in the treatment of various types of malignant tumors. It belongs to the class of drugs known as tyrosine kinase inhibitors, which work by blocking the action of certain proteins that signal cancer cells to grow and divide.
Mechanism of Action[edit | edit source]
Zeteletinib functions as a tyrosine kinase inhibitor, specifically targeting the epidermal growth factor receptor (EGFR). EGFR is a protein found on the surface of some cells and to which epidermal growth factor binds, causing the cells to divide. By inhibiting the action of EGFR, Zeteletinib can help to slow or stop the growth of cancer cells.
Clinical Trials[edit | edit source]
Zeteletinib is currently in the clinical trial phase of development. Early studies have shown promising results, with some patients experiencing a reduction in tumor size and improved survival rates. However, more research is needed to fully understand the drug's efficacy and safety profile.
Side Effects[edit | edit source]
As with all chemotherapy drugs, Zeteletinib has the potential to cause side effects. These may include nausea, vomiting, diarrhea, and fatigue. Patients may also experience skin reactions, such as rash or dry skin, due to the drug's mechanism of action.
Future Directions[edit | edit source]
The future of Zeteletinib as a cancer treatment will depend on the results of ongoing and future clinical trials. If these trials continue to show positive results, the drug could potentially be approved for use in the treatment of various types of cancer.
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Contributors: Prab R. Tumpati, MD