Zinc finger protein 727

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Ideogram human chromosome 7

Zinc finger protein 727

Zinc finger protein 727, also known as ZNF727, is a protein-coding gene located on chromosome 19 in humans. This gene encodes a zinc finger protein that plays a crucial role in various cellular processes. Zinc finger proteins are a class of proteins that bind to DNA and regulate gene expression.

Function[edit | edit source]

ZNF727 is involved in transcriptional regulation by binding to specific DNA sequences and modulating the expression of target genes. It contains multiple zinc finger domains that enable it to interact with DNA in a sequence-specific manner. Through these interactions, ZNF727 can activate or repress the transcription of downstream genes.

Clinical Significance[edit | edit source]

Mutations in the ZNF727 gene have been associated with certain genetic disorders and diseases. Dysregulation of ZNF727 expression has been linked to cancer, developmental disorders, and other pathological conditions. Further research is needed to fully understand the implications of ZNF727 dysfunction in human health.

Interactions[edit | edit source]

ZNF727 has been shown to interact with various proteins and transcription factors in the cell. These interactions are essential for its regulatory functions and contribute to the complex network of gene expression control. Understanding the protein-protein interactions of ZNF727 is crucial for deciphering its role in cellular processes.

References[edit | edit source]

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Contributors: Prab R. Tumpati, MD