Γ-Cyclodextrin

Gamma CD cone shape

== Γ-Cyclodextrin ==

Γ-Cyclodextrin is a type of cyclodextrin molecule that consists of eight glucose units linked together in a ring structure. It is a cyclic oligosaccharide with a cone-shaped geometry, making it useful for encapsulating guest molecules within its cavity.

Structure

The structure of Γ-cyclodextrin is characterized by its eight glucose units connected by α-1,4 glycosidic bonds. This arrangement results in a hydrophobic cavity that can accommodate various guest molecules, such as flavor compounds or fragrances, through host-guest interactions.

Applications

Γ-Cyclodextrin is commonly used in the food industry as a flavor encapsulation agent to improve the stability and solubility of sensitive compounds. It is also utilized in the pharmaceutical industry for drug delivery purposes, where it can enhance the bioavailability and efficacy of certain drugs. In addition, Γ-cyclodextrin has applications in the cosmetics industry for encapsulating active ingredients in skincare products, as well as in the agricultural sector for formulating pesticides and herbicides.

Synthesis

Γ-Cyclodextrin can be synthesized through enzymatic conversion of starch by specific enzymes known as cyclodextrin glycosyltransferases. This process involves the selective cleavage and rearrangement of glucose units to form the desired cyclic structure.

Safety

Γ-Cyclodextrin is generally recognized as safe (GRAS) by regulatory authorities for use in food and pharmaceutical applications. However, as with any food additive, it is important to adhere to recommended usage levels to ensure safety and efficacy.