Γ-Glutamylmethylamide
Γ-Glutamylmethylamide is a chemical compound that is part of the amino acid family. It is a derivative of glutamic acid, one of the 20 standard amino acids used in animal genes to synthesize proteins.
Chemical Structure[edit | edit source]
Γ-Glutamylmethylamide is a γ-glutamyl compound, which means it has a glutamyl group (a derivative of glutamic acid) attached to a methyl group via an amide bond. The γ-glutamyl group is attached to the α-carbon of the methyl group, forming a γ-glutamylmethylamide bond.
Biological Role[edit | edit source]
In biological systems, γ-glutamylmethylamide plays a role in the metabolism of glutamic acid. It is a substrate for the enzyme γ-glutamyltransferase, which catalyzes the transfer of the γ-glutamyl group from γ-glutamylmethylamide to other amino acids, peptides, and proteins. This process is part of the γ-glutamyl cycle, which is involved in the synthesis and degradation of glutathione, a critical antioxidant in cells.
Pharmacological Importance[edit | edit source]
Γ-Glutamylmethylamide has potential pharmacological importance due to its role in glutathione metabolism. Alterations in glutathione levels have been implicated in a variety of diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases. Therefore, compounds that can modulate glutathione levels, such as γ-glutamylmethylamide, may have therapeutic potential.
See Also[edit | edit source]
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
WikiMD's Wellness Encyclopedia |
Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD