Glutathione

Glutathione is a peptide molecule synthesized in the body from the amino acids L-cysteine, L-glutamic acid and glycine. The peptide is an antioxidant, preventing damage to important cellular components caused by reactive oxygen species such as free radicals and peroxides.

Structure and properties

Glutathione is a tripeptide with a gamma peptide linkage between the carboxyl group of the glutamate side chain and the amine group of cysteine. The carboxyl group of the cysteine is attached by normal peptide linkage to glycine. Its chemical structure is HO2CCH(NH2)CH2C(O)NHCH(C(O)NH2)CH2CO2H.

Function

Glutathione is involved in various processes in the body, including:

• Tissue building and repair
• Making chemicals and proteins needed in the body
• Supporting the immune system
• Forming antioxidants that prevent cellular damage
• Detoxification of the body

Health implications

Glutathione has potential implications in health and disease. It is used in the treatment of cancer, HIV, Parkinson's disease, sickle cell anemia, diabetes, and more. However, more research is needed to fully understand its effects and potential uses.

See also

• Antioxidant
• Amino acid
• Peptide

Glutathione Resources
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