Equol

From WikiMD's Wellness Encyclopedia

(Redirected from (S)-Equol)

Equol is a metabolite of isoflavones, a type of phytoestrogen, that is produced by the action of gut microbiota. It is a non-steroidal estrogen that has been the subject of numerous studies due to its potential health benefits, particularly in relation to menopause, osteoporosis, and cardiovascular disease.

History[edit | edit source]

Equol was first isolated in 1982 from the urine of individuals who consumed soy products. It was named after the chemical structure of the compound, which is a 7-hydroxy-3-(4'-hydroxyphenyl)-chroman.

Production[edit | edit source]

Equol is produced in the gut by the action of certain types of bacteria, including Lactobacillus and Bifidobacterium. These bacteria convert dietary isoflavones, particularly daidzein, into equol.

Health Benefits[edit | edit source]

Numerous studies have suggested that equol may have a number of health benefits. These include:

  • Menopause: Equol has been shown to alleviate some of the symptoms of menopause, including hot flashes and night sweats.
  • Osteoporosis: Some research suggests that equol may help to prevent bone loss and reduce the risk of osteoporosis.
  • Cardiovascular Disease: Equol may help to reduce the risk of cardiovascular disease by improving blood vessel function and reducing inflammation.

Safety and Side Effects[edit | edit source]

Equol is generally considered safe, with few reported side effects. However, as with any supplement, it should be used under the supervision of a healthcare provider.

See Also[edit | edit source]

Equol Resources

Contributors: Prab R. Tumpati, MD