Equol
(Redirected from (S)-Equol)
Equol is a metabolite of isoflavones, a type of phytoestrogen, that is produced by the action of gut microbiota. It is a non-steroidal estrogen that has been the subject of numerous studies due to its potential health benefits, particularly in relation to menopause, osteoporosis, and cardiovascular disease.
History[edit | edit source]
Equol was first isolated in 1982 from the urine of individuals who consumed soy products. It was named after the chemical structure of the compound, which is a 7-hydroxy-3-(4'-hydroxyphenyl)-chroman.
Production[edit | edit source]
Equol is produced in the gut by the action of certain types of bacteria, including Lactobacillus and Bifidobacterium. These bacteria convert dietary isoflavones, particularly daidzein, into equol.
Health Benefits[edit | edit source]
Numerous studies have suggested that equol may have a number of health benefits. These include:
- Menopause: Equol has been shown to alleviate some of the symptoms of menopause, including hot flashes and night sweats.
- Osteoporosis: Some research suggests that equol may help to prevent bone loss and reduce the risk of osteoporosis.
- Cardiovascular Disease: Equol may help to reduce the risk of cardiovascular disease by improving blood vessel function and reducing inflammation.
Safety and Side Effects[edit | edit source]
Equol is generally considered safe, with few reported side effects. However, as with any supplement, it should be used under the supervision of a healthcare provider.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD