1,4,6-Androstatriene-3,17-dione

From WikiMD's Food, Medicine & Wellnesspedia

What is 1,4,6-Androstatriene-3,17-dione?[edit | edit source]

1,4,6-androstatrien-3,17-dione
  • Androsta-1,4,6-triene-3,17-dione is an androstanoid that is androsta-1,4,6-triene substituted by oxo groups at positions 3 and 17.
  • It is a 17-oxo steroid, an androstanoid and a 3-oxo-Delta(1),Delta(4)-steroid.
  • IUPAC Name: (8R,9S,10R,13S,14S)-10,13-dimethyl-9,11,12,14,15,16-hexahydro-8H-cyclopenta[a]phenanthrene-3,17-dione
  • InChI: InChI=1S/C19H22O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h3-4,7,9,11,14-16H,5-6,8,10H2,1-2H3/t14-,15-,16-,18-,19-/m0/s1
  • InChI Key: DKVSUQWCZQBWCP-QAGGRKNESA-N
  • Canonical SMILES: CC12CCC3C(C1CCC2=O)C=CC4=CC(=O)C=CC34C
  • Isomeric SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)C=CC4=CC(=O)C=C[C@]34C
  • Molecular formula: C19H22O2
  • Molecular weight: 282.4 g·mol−1
  • Synonyms:
  1. Androsta-1,4,6-triene-3,17-dione
  2. 633-35-2
  3. 1,4,6-Androstatrien-3,17-dione
  4. 1,4,6-Etioallochan-dione
  5. UNII-217A6T1V8N
  6. CHEMBL2311178
  7. 217A6T1V8N
  8. (8R,9S,10R,13S,14S)-10,13-dimethyl-9,11,12,14,15,16-hexahydro-8H-cyclopenta[a]phenanthrene-3,17-dione
  9. 1,4,6-Andorstatriene-3,17-dione
  10. A146-T317D
  11. ATD
  12. SCHEMBL132874
  13. DTXSID60862328
  14. CHEBI:131190
  15. ZINC4074121
  16. BDBM50421878
  17. AKOS030240786
  18. HY-136092
  19. CS-0119570
  20. Q4545687

How does this drug work?[edit | edit source]

It is an EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor which interferes with the action of aromatase (EC 1.14.14.14) and so reduces production of estrogenic steroid hormones.

Wiki.png

Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD


Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro) available.
Advertise on WikiMD

WikiMD is not a substitute for professional medical advice. See full disclaimer.

Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.


Contributors: Bonnu