1,4-Bis(diphenylphosphino)butane

1,4-Bis(diphenylphosphino)butane (dppb) is a chemical compound used as a ligand in the field of inorganic chemistry. It is a white, crystalline solid at room temperature and is soluble in common organic solvents.

Structure and Bonding

The molecule of 1,4-Bis(diphenylphosphino)butane consists of a four-carbon alkane chain with a diphenylphosphino group attached to each of the terminal carbons. The phosphorus atoms are trivalent, forming two bonds with the phenyl groups and one with the butane chain. The molecule is flexible due to the rotation around the carbon-phosphorus bonds.

Synthesis

1,4-Bis(diphenylphosphino)butane can be synthesized by the reaction of chlorodiphenylphosphine with 1,4-dibromobutane in the presence of a base. The reaction proceeds via nucleophilic substitution, with the phosphine acting as the nucleophile.

Applications

1,4-Bis(diphenylphosphino)butane is primarily used as a ligand in the synthesis of transition metal complexes. These complexes are used in various applications, including catalysis, molecular recognition, and material science.

Safety

As with many organophosphorus compounds, 1,4-Bis(diphenylphosphino)butane is toxic and should be handled with care. It can cause irritation to the skin, eyes, and respiratory tract.

See also

• Phosphine
• Organophosphorus chemistry
• Ligand