From WikiMD's Food, Medicine & Wellness Encyclopedia

1-Tetracosanol Structural Formula V1

1-Tetracosanol, also known as lignoceryl alcohol, is a fatty alcohol with the chemical formula C24H50O. It is a saturated long-chain alcohol found in a variety of natural sources, including the waxes of plants such as carnauba wax and in the cuticles of insects. 1-Tetracosanol is of interest in various fields including biochemistry, nutrition, and pharmacology, due to its potential health benefits and applications in different industries.

Sources and Production[edit | edit source]

1-Tetracosanol is primarily obtained from natural sources. It is present in the waxes of certain plants, notably in carnauba wax, which is derived from the leaves of the Brazilian palm tree Copernicia prunifera. It can also be found in the cuticles of some insects, serving as a component of their protective wax layer. Additionally, 1-Tetracosanol can be synthesized through the hydrogenation of lignoceric acid or by the reduction of tetracosanoic acid in the laboratory.

Properties[edit | edit source]

As a long-chain fatty alcohol, 1-Tetracosanol is a white, waxy solid at room temperature. It is insoluble in water but soluble in nonpolar organic solvents such as hexane and chloroform. Its physical and chemical properties make it useful in various industrial applications, including the production of cosmetics, pharmaceuticals, and protective coatings.

Applications[edit | edit source]

      1. Industrial Uses ###

1-Tetracosanol is utilized in the manufacture of cosmetics, pharmaceuticals, and lubricants. In cosmetics, it is valued for its ability to form protective barriers on the skin and hair, as well as for its emollient properties. In the pharmaceutical industry, it is used in the formulation of certain drugs and as a base for ointments.

      1. Health Benefits ###

Research has suggested that 1-Tetracosanol may have several health benefits, including anti-inflammatory and cholesterol-lowering effects. It has been studied for its potential to improve exercise performance and endurance by enhancing muscle function. However, further research is needed to fully understand its mechanisms of action and to confirm these health benefits in humans.

Safety and Toxicology[edit | edit source]

1-Tetracosanol is generally considered safe for use in cosmetics and pharmaceuticals. It is non-toxic and non-irritating to the skin and eyes in standard applications. However, as with any chemical substance, appropriate safety measures should be taken when handling pure 1-Tetracosanol to avoid inhalation or ingestion.


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Contributors: Prab R. Tumpati, MD