16β,17α-Epiestriol
16β,17α-Epiestriol is a steroid hormone and a minor metabolite of estriol. It is one of the many estrogens, which are a group of hormones that play an essential role in the development and regulation of the female reproductive system and secondary sexual characteristics.
Chemical Structure and Properties[edit | edit source]
16β,17α-Epiestriol is a steroid with the chemical formula C18H24O3. It is structurally similar to estriol, differing only in the configuration of the hydroxyl groups at the 16 and 17 positions. The compound has a molecular weight of 288.38 g/mol.
Biosynthesis and Metabolism[edit | edit source]
16β,17α-Epiestriol is synthesized in the body from estriol, which itself is derived from estrone and estradiol. The conversion involves the action of various enzymes that modify the steroid nucleus and the attached functional groups. This metabolite is typically found in small quantities in the urine of pregnant women, as it is a byproduct of the metabolism of estriol.
Biological Activity[edit | edit source]
As an estrogen, 16β,17α-Epiestriol binds to estrogen receptors in various tissues, including the uterus, breast, and bone. However, its biological activity is significantly lower than that of the primary estrogens, estradiol and estrone. The exact physiological role of 16β,17α-Epiestriol is not well understood, but it is believed to contribute to the overall estrogenic activity in the body.
Clinical Significance[edit | edit source]
The presence of 16β,17α-Epiestriol in the urine can be used as a marker for certain physiological and pathological conditions. Elevated levels may indicate increased estrogen metabolism, which can occur during pregnancy or in certain endocrine disorders. However, due to its minor role, it is not commonly used as a primary diagnostic marker.
Research and Applications[edit | edit source]
Research on 16β,17α-Epiestriol is limited compared to other estrogens. Studies have focused on its role in estrogen metabolism and its potential effects on various tissues. Understanding its function could provide insights into the complex interactions of steroid hormones in the body.
See Also[edit | edit source]
References[edit | edit source]
This hormone-related article is a stub. You can help WikiMD by expanding it.
Transform your life with W8MD's budget GLP1 injections from $125
W8MD offers a medical weight loss program NYC and a clinic to lose weight in Philadelphia. Our W8MD's physician supervised medical weight loss centers in NYC provides expert medical guidance, and offers telemedicine options for convenience.
Why choose W8MD?
- Comprehensive care with FDA-approved weight loss medications including:
- loss injections in NYC both generic and brand names:
- weight loss medications including Phentermine, Qsymia, Diethylpropion etc.
- Accept most insurances for visits or discounted self pay cost.
- Generic weight loss injections starting from just $125.00 for the starting dose
- In person weight loss NYC and telemedicine medical weight loss options in New York city available
- Budget GLP1 weight loss injections in NYC starting from $125.00 biweekly with insurance!
Book Your Appointment
Start your NYC weight loss journey today at our NYC medical weight loss, and Philadelphia medical weight loss Call (718)946-5500 for NY and 215 676 2334 for PA
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's NYC physician weight loss.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available. Call 718 946 5500.
Advertise on WikiMD
WikiMD's Wellness Encyclopedia |
Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD