Estriol

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Estriol is a type of estrogen, which is a group of hormones that play an important role in the female reproductive system. While estriol is produced by the placenta during pregnancy, it is also produced in small amounts by the ovaries and adrenal glands in non-pregnant women.

Production and Function[edit | edit source]

Estriol is produced primarily during pregnancy, with the placenta being the main site of production. The placenta produces estriol from dehydroepiandrosterone (DHEA), a hormone that is produced by the adrenal glands and the liver. The levels of estriol in the body increase throughout pregnancy, reaching their peak just before birth.

In non-pregnant women, estriol is produced in small amounts by the ovaries and adrenal glands. It is also produced in the liver from estrone and estradiol, two other types of estrogen.

The main function of estriol is to promote the growth and development of the female reproductive system. It also plays a role in maintaining pregnancy and preparing the body for childbirth.

Measurement[edit | edit source]

The levels of estriol in the body can be measured using a blood or urine test. This is often done during pregnancy to monitor the health of the baby and the placenta. Low levels of estriol can indicate a problem with the baby or the placenta, while high levels can indicate a multiple pregnancy (twins or triplets).

Health Effects[edit | edit source]

While estriol is necessary for normal female reproductive function, abnormal levels can have negative health effects. High levels of estriol can increase the risk of breast cancer and endometrial cancer, while low levels can lead to osteoporosis and heart disease.

See Also[edit | edit source]

Estriol Resources
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Contributors: Prab R. Tumpati, MD