1T-LSD

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1T-LSD is a psychedelic drug and a derivative of lysergic acid diethylamide (LSD). It is part of the lysergamide family and is considered a research chemical. It is not to be confused with LSD, as 1T-LSD has a slightly different chemical structure, which impacts its pharmacology and effects.

Chemistry[edit | edit source]

1T-LSD, or 1-propionyl-lysergic acid diethylamide, is a semi-synthetic molecule of the lysergamide class. The structure of 1T-LSD is very similar to LSD, with an N,N-diethylamide functional group bound to R8 of the chemical structure. However, 1T-LSD is different from LSD by having a propionyl group attached to the nitrogen molecule of the polycyclic indole group of LSD.

Pharmacology[edit | edit source]

The exact pharmacology of 1T-LSD is not fully understood. However, it is believed to act as a 5-HT2A receptor agonist, similar to other psychedelic drugs. This receptor is involved in cognitive processes in the prefrontal cortex, which could explain the cognitive effects of 1T-LSD. However, more research is needed to fully understand the pharmacological profile of this substance.

Effects[edit | edit source]

The effects of 1T-LSD are reported to be similar to those of LSD, including hallucinations, altered thinking processes, closed and open eye visuals, synesthesia, an altered sense of time, and spiritual experiences. The effects typically last for 6-10 hours, with the peak effects occurring 2-4 hours after ingestion.

Legal Status[edit | edit source]

The legal status of 1T-LSD varies by country. In some countries, it is a controlled substance, while in others it is legal to possess for personal use. It is always important to check the legal status in your specific location before possession or use.

See Also[edit | edit source]

References[edit | edit source]

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Contributors: Prab R. Tumpati, MD