5-HT2A receptor

5-HT2A receptor is a subtype of the 5-HT2 receptor that belongs to the serotonin receptor family and is a G protein-coupled receptor. This receptor is linked to various psychiatric disorders, including schizophrenia, depression, and anxiety.

Function

The 5-HT2A receptor is known for its significant role in the functioning of the central nervous system. It is involved in various brain functions, such as the regulation of mood, anxiety, sleep, and cognition.

Clinical significance

The 5-HT2A receptor is thought to be a key receptor in the effect of many hallucinogens, antipsychotic, and antidepressant drugs.

Pharmacology

Various drugs target the 5-HT2A receptor for different therapeutic purposes. For instance, antipsychotic drugs are often 5-HT2A antagonists, while some psychedelic drugs are 5-HT2A agonists.

See also

• 5-HT receptor
• Serotonin
• G protein-coupled receptor

References

5-HT2A receptor Resources
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