ALD-52

ALD-52, also known as 1-acetyl-LSD, is a chemical analogue of lysergic acid diethylamide (LSD). It was originally discovered by Albert Hofmann, but was not widely studied until the rise in popularity of psychedelics in the 1960s.

History[edit | edit source]

ALD-52 was first synthesized by Albert Hofmann in his study of LSD analogues, but its potential use in psychotherapy was not recognized until the 1960s. It was then further studied by Alexander Shulgin and described in his book TiHKAL.

Chemistry[edit | edit source]

ALD-52 is a derivative of LSD, with the key difference being the addition of an acetyl group. This makes it a structural analogue of LSD, and it is often referred to as "1-acetyl-LSD".

Pharmacology[edit | edit source]

Like LSD, ALD-52 acts as a partial agonist at the 5-HT2A receptor. The psychedelic effects are believed to come from ALD-52's efficacy at the 5-HT2A receptors distributed throughout the brain. ALD-52 is thought to be metabolized into LSD in the body, which would mean that the two drugs are likely to have very similar pharmacological properties.

Effects[edit | edit source]

The effects of ALD-52 are nearly identical to those of LSD. Both are powerful hallucinogens that can produce profound changes in consciousness, perception, and mood. Users often report intense visual hallucinations, altered thinking processes, and a distorted sense of time.

Legal status[edit | edit source]

ALD-52 is illegal in many countries, including the United States, where it is classified as a Schedule I drug under the Controlled Substances Act. However, it is legal in some countries, including Canada and the United Kingdom.

See also[edit | edit source]

ALD-52 Resources
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