From WikiMD's Food, Medicine & Wellness Encyclopedia

2,5-Dimethoxy-4-nitroamphetamine (DOx series), also known as Aleph-7, is a psychedelic drug and a member of the amphetamine family. It is one of the most potent compounds in the DOx series, known for its hallucinogenic and psychedelic effects.

Chemistry[edit | edit source]

2,5-Dimethoxy-4-nitroamphetamine is a synthetic molecule of the amphetamine class. Molecules of this class contain a phenethylamine core featuring a phenyl ring bound to an amino (NH2) group through an ethyl chain with an additional methyl substitution at Rα.

Pharmacology[edit | edit source]

The mechanism that produces the hallucinogenic and entheogenic effects of 2,5-Dimethoxy-4-nitroamphetamine is thought to result primarily from 5-HT2A receptor agonism. However, the role of these interactions and how they result in the psychedelic experience continues to remain elusive.

Effects[edit | edit source]

The effects of 2,5-Dimethoxy-4-nitroamphetamine are similar to other drugs in the DOx series and include open and closed eye visuals, time distortion, enhanced introspection, and euphoria.

Risks[edit | edit source]

As with all psychedelics, there are several physical and psychological risks associated with the use of 2,5-Dimethoxy-4-nitroamphetamine. These include potential for overstimulation, panic attacks, and psychosis in those predisposed.

Legality[edit | edit source]

2,5-Dimethoxy-4-nitroamphetamine is a Schedule I controlled substance in the United States, meaning it is illegal to manufacture, buy, possess, or distribute without a DEA license.

See also[edit | edit source]


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Contributors: Prab R. Tumpati, MD