From WikiMD's Food, Medicine & Wellness Encyclopedia

2,5-Dimethoxy-4-bromoamphetamine (also known as DOB) is a psychedelic drug that is part of the amphetamine class. It is known for its powerful hallucinogenic effects, which can last up to 30 hours.

Chemistry[edit | edit source]

DOB is a substituted amphetamine, meaning it is an amphetamine molecule that has been modified. In this case, it has been substituted with a bromine atom at the 4 position of the phenyl ring, and two methoxy groups at the 2 and 5 positions. This gives it its full chemical name of 2,5-dimethoxy-4-bromoamphetamine.

Pharmacology[edit | edit source]

The exact mechanism of action of DOB is not fully understood, but it is believed to work primarily by binding to the serotonin 2A receptor (5-HT2A receptor), which plays a key role in the regulation of mood, anxiety, and perception. This receptor is also the target of other psychedelic drugs, such as LSD and psilocybin.

Effects[edit | edit source]

The effects of DOB can vary greatly depending on the dose, the individual's physiology, and the setting in which it is taken. Common effects include visual hallucinations, enhanced perception of colors and sounds, altered sense of time, and feelings of euphoria. However, it can also cause negative effects such as anxiety, paranoia, and physical discomfort.

Risks[edit | edit source]

Like all psychedelic drugs, DOB carries risks. These include psychological risks, such as triggering latent mental health issues, and physical risks, such as hypertension and tachycardia. It is also possible to overdose on DOB, although this is rare.

Legal Status[edit | edit source]

The legal status of DOB varies by country. In the United States, it is classified as a Schedule I controlled substance, meaning it is illegal to manufacture, distribute, or possess.

See Also[edit | edit source]


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Contributors: Prab R. Tumpati, MD