5F-AB-PINACA
5F-AB-PINACA[edit | edit source]
5F-AB-PINACA is a synthetic cannabinoid that has been used as a designer drug. It is a potent agonist of the cannabinoid receptors, specifically the CB1 receptor and CB2 receptor.
Chemical Structure[edit | edit source]
5F-AB-PINACA is chemically classified as an indazole-based synthetic cannabinoid. Its structure includes a 5-fluoropentyl chain, which is a common feature in many synthetic cannabinoids, contributing to its high potency and affinity for cannabinoid receptors.
Pharmacology[edit | edit source]
5F-AB-PINACA acts as a full agonist at the CB1 and CB2 receptors, which are part of the endocannabinoid system. This system is involved in regulating various physiological processes, including mood, memory, and pain sensation. The activation of these receptors by 5F-AB-PINACA can lead to psychoactive effects similar to those of tetrahydrocannabinol (THC), the active component of cannabis.
Effects[edit | edit source]
The effects of 5F-AB-PINACA can include euphoria, relaxation, altered perception, and increased appetite. However, due to its high potency, it can also cause adverse effects such as anxiety, paranoia, tachycardia, and in severe cases, psychosis or seizures.
Legal Status[edit | edit source]
Due to its potential for abuse and lack of medical use, 5F-AB-PINACA has been classified as a controlled substance in many countries. It is often included in the list of substances banned under synthetic drug laws.
Synthesis[edit | edit source]
The synthesis of 5F-AB-PINACA involves the reaction of an indazole core with a fluorinated alkyl chain. This process requires specialized knowledge in organic chemistry and access to specific reagents and equipment.
Health Risks[edit | edit source]
The use of 5F-AB-PINACA has been associated with numerous health risks, including acute intoxication and long-term psychological effects. Users may experience severe withdrawal symptoms, and there is a risk of developing substance use disorder.
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