5F-AB-FUPPYCA

5F-AB-FUPPYCA is a synthetic cannabinoid that is derived from the cannabis plant. It is a potent agonist for the CB1 receptor, and is used in the research of cannabinoid receptor agonists. 5F-AB-FUPPYCA shares a close structural relationship with a series of designer drugs that are known as FAB-144 and FUB-144.

Chemistry

5F-AB-FUPPYCA is a synthetic cannabinoid that features a fluorobenzyl group at the 1-amino-3-methyl-1-oxobutane moiety. It is an analogue of AB-FUBINACA, which features a terminal amide group on the valine residue.

Pharmacology

5F-AB-FUPPYCA is a potent agonist for the CB1 receptor, with a Ki of 0.9 nM and an EC50 of 1.8 nM. It is selective for the CB1 receptor over the CB2 receptor, with a selectivity ratio of 80:1.

Legality

In the United States, 5F-AB-FUPPYCA is a Schedule I controlled substance. It is also controlled in China.

See also

• AB-FUBINACA
• FAB-144
• FUB-144
• Synthetic cannabinoids
• Cannabinoid receptor agonist

References

5F-AB-FUPPYCA Resources
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