4-HO-DiPT

4-HO-DiPT (also known as 4-Hydroxy-N,N-diisopropyltryptamine) is a psychedelic drug and a lesser-known psychedelic tryptamine. It is structurally related to psilocin, psilocybin, and DMT and is reported to have similar effects.

Chemistry

4-HO-DiPT is a synthetic compound of the tryptamine class. Tryptamines share a core structure comprised of a bicylic indole heterocycle attached at R3 to an amino group via an ethyl side chain. 4-HO-DiPT is substituted at R4 of its indole heterocycle with a hydroxyl functional group OH−. It also contains two isopropyl groups bound to the terminal amine RN of its tryptamine backbone.

Pharmacology

The pharmacology of 4-HO-DiPT is not fully understood. Like other psychedelics, it is thought to act primarily by binding to serotonin receptors in the brain, particularly the 5-HT2A receptor. The psychoactive effects are believed to come from 4-HO-DiPT's efficacy at the 5-HT2A receptors. However, the role of these interactions and how they result in the psychedelic experience continues to remain an object of scientific elucidation.

Effects

The effects of 4-HO-DiPT are similar to other psychedelic tryptamines but with a relatively short duration. Users report the onset of effects within 20 to 30 minutes of ingestion, peaking within one to two hours, and completely fading after four to six hours. Effects can include auditory distortion, intense visual hallucinations, and altered perception of time. Like all psychedelics, it can also cause nausea, pupil dilation, and increased heart rate.

Legality

The legality of 4-HO-DiPT varies by country. In the United States, it is not controlled at the federal level, but it could be considered an analog of psilocin under the Federal Analogue Act. In the United Kingdom, it is a Class A drug under the Misuse of Drugs Act 1971.

See also

• Tryptamine
• Psychedelic drug
• Serotonin receptor