Lysergic acid 2-butyl amide

Lysergic acid 2-butyl amide

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Chemical structure of Lysergic acid 2-butyl amide

Lysergic acid 2-butyl amide, also known as LSB, is a chemical compound that belongs to the family of lysergamides. It is derived from lysergic acid and is structurally similar to lysergic acid diethylamide (LSD). LSB is known for its psychedelic properties and has been used recreationally for its hallucinogenic effects.

History

LSB was first synthesized in the laboratory by chemist Albert Hofmann in the 1960s. Hofmann, who is also known for his discovery of LSD, was experimenting with various lysergamides to explore their chemical and pharmacological properties. During his research, he discovered the synthesis of LSB and noted its unique psychoactive effects.

Chemical Properties

LSB has a molecular formula of C20H25N3O and a molecular weight of 323.44 g/mol. It is a white crystalline powder that is sparingly soluble in water but soluble in organic solvents such as ethanol and chloroform. The compound has a melting point of approximately 180-185 °C.

Pharmacology

LSB acts as a serotonin receptor agonist, specifically targeting the 5-HT2A receptor subtype. It binds to these receptors in the brain, leading to altered perception, mood changes, and hallucinations. The exact mechanism of action of LSB is not fully understood, but it is believed to modulate the activity of serotonin, a neurotransmitter involved in regulating mood, perception, and cognition.

Effects

The effects of LSB are similar to those of LSD and other hallucinogens. Users typically experience visual distortions, changes in perception of time and space, enhanced creativity, and an altered sense of self. The intensity and duration of these effects can vary depending on the dose and individual sensitivity.

Legality

The legal status of LSB varies from country to country. In some jurisdictions, it is classified as a controlled substance and is illegal to possess, produce, or distribute. In other places, it may be unregulated or considered a legal gray area. It is important to check the specific laws and regulations of your country or region before engaging in any activities involving LSB.

Safety and Precautions

The use of LSB carries potential risks and should be approached with caution. Due to its hallucinogenic properties, it can induce intense psychological experiences that may be overwhelming for some individuals. It is advisable to use LSB in a safe and controlled environment, preferably with a trusted companion. Additionally, individuals with a history of mental health conditions or those taking medications that interact with serotonin should avoid using LSB.