25C-NBF

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25C-NBF is a psychedelic phenethylamine and derivative of 2C-C which was discovered in 2014 by a team at Purdue University. It is part of the 25x-NBx series, a group of compounds derived from the 2C family of psychedelics.

Chemistry[edit | edit source]

25C-NBF is a derivative of 2C-C, which itself is a psychedelic phenethylamine. The full chemical name of 25C-NBF is 2-(4-chloro-2,5-dimethoxyphenyl)-N-[(2-fluorophenyl)methyl]ethanamine. It has a molar mass of 349.86 g/mol and a molecular formula of C17H20ClFNO2.

Pharmacology[edit | edit source]

The exact mechanism of action of 25C-NBF is not fully understood. However, it is believed to work primarily by acting as a 5-HT2A receptor agonist, similar to other psychedelic phenethylamines. This receptor is involved in the regulation of mood, anxiety, and perception, and its activation can lead to hallucinogenic effects.

Effects[edit | edit source]

The effects of 25C-NBF can vary greatly depending on the dose, individual physiology, and set and setting. However, common effects reported by users include visual hallucinations, enhanced colors, altered thought patterns, euphoria, and increased empathy and sociability. Some users also report experiencing negative effects such as anxiety, paranoia, and uncomfortable body sensations.

Legality[edit | edit source]

As of 2021, 25C-NBF is a controlled substance in many countries, including the United States, where it is classified as a Schedule I drug under the Controlled Substances Act. This means it is illegal to manufacture, distribute, or possess without a license.

Safety[edit | edit source]

Due to its relatively recent discovery and lack of extensive human research, the safety profile of 25C-NBF is largely unknown. However, like other psychedelics, it is thought to have a low toxicity relative to dose. Nevertheless, potential risks include psychological distress, dangerous behavior due to altered perceptions, and rare cases of severe physical reactions.

See also[edit | edit source]

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Contributors: Prab R. Tumpati, MD