25I-NBOMe
25I-NBOMe (also known as 2C-I-NBOMe, Cimbi-5 and 25I) is a psychedelic hallucinogen that is used in biochemistry research for mapping the brain's usage of the type 2A serotonin receptor; it is also sometimes used for recreational purposes. A derivative of the phenethylamine 2C-I family, it is the most well-known member of the 25-NB family. It has been used in humans as a radioligand in SPECT imaging to map the distribution of 5-HT2A receptors in the brain.
History[edit | edit source]
25I-NBOMe was discovered in 2003 by Ralf Heim at the Free University of Berlin. It was further researched by a team at Purdue University led by David Nichols. The team was studying the benzyl substitution of 2C-I and its effects.
Pharmacology[edit | edit source]
25I-NBOMe is a full agonist of the human 5-HT2A receptor, which means it fully activates the receptor. The specific binding of 25I-NBOMe to the 5-HT2A receptor is thought to cause its psychedelic effects.
Effects[edit | edit source]
The effects of 25I-NBOMe can be very diverse and can range from euphoria to extreme hallucinations. The effects can last from six to ten hours, and can be followed by a period of insomnia.
Legal status[edit | edit source]
The legal status of 25I-NBOMe varies by country and is a controlled substance in many countries.
See also[edit | edit source]
References[edit | edit source]
| 25I-NBOMe Resources | |
|---|---|
|
 |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
