Bufotenin
Bufotenin is a tryptamine related to the neurotransmitters serotonin, melatonin, and dimethyltryptamine. The name bufotenin originates from the Bufo genus of toads, which secrete bufotoxins from their glands.
Chemistry[edit | edit source]
Bufotenin is a member of the class of compounds known as tryptamines, which are derived from the amino acid tryptophan. It is a alkaloid and a monoamine.
Pharmacology[edit | edit source]
Bufotenin is a serotonin receptor agonist, which means it can activate serotonin receptors in the brain. It is also a monoamine oxidase inhibitor (MAOI), which means it can increase the levels of monoamines in the brain by inhibiting their breakdown.
Natural occurrence[edit | edit source]
Bufotenin is found in several species of toads, mushrooms, higher plants, and mammals. It is most commonly known for its presence in the skin and venom of toads belonging to the Bufo genus.
Effects[edit | edit source]
The effects of bufotenin are primarily psychedelic and can include hallucinations, changes in perception, euphoria, and nausea. However, the effects can vary greatly depending on the dose and individual's sensitivity.
Legal status[edit | edit source]
The legal status of bufotenin varies by country. In some countries, it is classified as a controlled substance, while in others it is legal.
See also[edit | edit source]
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Contributors: Prab R. Tumpati, MD
